Today I had a conversation with Reza Naghii, PhD, a researcher at the University of Medical Sciences in Iran. Naghii and his colleagues published a study in 2010 (1) which suggests that supplementation with boron for 7 days increases testosterone. The subjects in the study were healthy, non-smoking males, 29-50 years of age (avg. ~41). For each of the 7 days, they received a capsule containing 10 mg of boron in the form of sodium tetraborate along with their breakfast. As I was writing this post, I actually received an email from Naghii. In it, he talks about how boron supplementation may increase testosterone, and its potential value to bodybuilders and others hoping to benefit from it.
“I believe boron is involved in hydroxylation process which produces active form of hormones and it acts better in people with a deficiency state, e.g. aged subjects or postmeopausal women. But still I would recommend it to bodybuilders instead of steroids. It needs confirmation and deserves a research work among the bodybuilders. Limited results indicates its effect on increasing Vit d which requires hydroxylation for production and activation. In my study in a week , we found: an increase of Free T. from 11.8 to 15.18 pg/ml and Estradiol decrease from 42 to 25 pg/ml. It seems a shift from estradiol production into [the direction of] free testosterone, or higher androgenicity after one week.”
https://robthoburn.wordpress.com/2011/02/02/boron-increases-testosterone-again/