Stukje over Candida die de toxinen Ethanol en Acetaldehyde produceert
Consequences of Ethanol and Acetaldehyde Poisoning
The consequences of chronic ethanol and acetaldehyde ingestion are well known as they occur in alcoholism. So assuming I do have a gut full of Candida/yeast acting as my own personal brewery, many of the effects are the same as those suffered by an alcoholic. At this stage it is worth knowing that ethanol is first converted by the body into acetaldehyde before that is itself converted into non-toxic acetic acid.
Here are some of the effects of ethanol:
Ethanol metabolism interferes with energy metabolism; this results in fatigue and buildup of lactic acid, causing muscle aches.
Hypoglycaemia or "low blood sugar" also results from the above.
Nutritional deficiencies - particularly but not limited to vitamins B1 (thiamine), B6 (pyridoxine), vitamin B9 (folic acid), B12 (cobalamin ), zinc, magnesium, potassium, and molydenum.
Anaemia due to folic acid and B12 deficiencies.
Gastrointestinal ulcers and increased intestinal permeability (leaky gut syndrome). Ethanol is highly toxic to all GI tract cells. Leaky gut syndrome is implicated in many diseases including food allergies/intolerances, systemic allergies, autoimmune disorders, chronic fatigue syndrome etc.
Here are some of the effects of acetaldehyde (significantly more toxic than ethanol):
Is responsible for most of the symptoms of a hangover. Causes dilation of blood vessels in the brain which result in the characteristic severe headaches.
Attacks and forms complexes with many proteins and nucleic acid (as in DNA and RNA) disrupting their normal functions.
Blocks secretion of proteins by the liver and causes swelling of hepatocytes (liver cells).
Binds and inactivates glutathione - the body's main antioxidant - thus increasing oxidative stress and allowing free radicals to damage cells throughout the body. Mitochondria, the energy producing machinery within each cell, are particularly susceptible to free radical damage.
Impairs the function of lymphocytes (an important type of white blood cell) and red blood cells (those that transport oxygen).
Increases the release of adrenaline causes heart palpitations, anxiety etc.
In addition both substances result in liver disease when the liver has to deal with them chronically and in sufficient amounts. They cause the buildup of fat in the liver impairing its function. The liver is the most metabolically active organ in the body and so an inefficient liver interferes with the production of bile (and therefore fat digestion), the production and detoxification of steroid hormones, and the detoxifcation of a huge range of substances such as ammonia from protein metabolism and gut bacteria, drugs, and pollutants.
You are obviously aware of the effects of alcohol on the brain so imagine dealing with symptoms such as confusion, forgetfulness, lack of concentration, mood swings etc, constantly, on a day to day basis. As well as the direct effects of alcohol and acetaldehyde on the brain they also have indirect effects. For example pyridoxine is required for the production of many neurotransmitters that regulate mood such as serotonin and noradrenaline, while the activated form of vitamin D is also required for their production. It is the liver's job to activate vitamin D so a poorly functioning liver due to ethanol and acetaldehyde poisoning can result in mood disorders through this mechanism.
I would also hypothesise that my development of multiple chemical sensitivity (MCS) a couple of years after the symptoms of severe intoxication began was a result of ethanol and acetaldehyde poisoning. It has been proposed that MCS is due to an acquired hypersensitivity to a group of chemical that would include ethanol and acetaldehyde subsequent to either acute or chronic poisoning with these or related compounds (e.g. formaldehyde).6
http://www.ei-resource.org/articles...l-chronic-ethanol-and-acetaldehyde-poisoning/