Mark, Edwin en de rest..
Ik ben benieuwd naar jullie supplementen on round en off round. Gebruiken jullie voldoende antioxidanten?
Edwin, heb je geprobeerd om korter dan 3uur te doseren?
Hier zegt Cutler dit:http://onibasu.com/archives/am/92631.html
at half time (1.5 hours) you could use a regular dose.
Actually many people tolerate higher doses if given more often. But I
didn't want to go into that in great detail because it would confuse
eveyrone. The 3 hour rule is somewhat of a practical compromise.
More often is always better, and surprisingly you can often make it
quite frequent and INCREASE the dose! But there is no fixed rule
here, and actually doing 2 or 1.5 or 1 hour dosing is REALLY A GIANT
PAIN!!!! So I don't recommend it unless 3 hour dosing is poorly
tolerated.
En hier: http://onibasu.com/archives/am/101625.html
The answer is a little more complicated than some may think.
MORE frequent dosing works better in the very sensitive people.
LESS frequent dosing works worse.
The actual amount of the dose is far less important than the frequency.
People who can't tolerate 10 mg every 4 hours often can take 100 mg
hourly and be fine. I have many cases doing exactly this.
Most doctors will agree that the ideal way to administer most
medications would be continuous intravenous infusion to keep blood
levels absolutely rock steady. However, this is impractical in most
cases. Simply taking the stuff by mouth often enough is a good enough
approximation to this to work in a lot of cases. "often enough"
depends somewhat on the individual. once a day is not often enough for
any chelator for any individual. 4 hours for DMSA is good enough for
most, but a few need it more often. Some coudl do 5 hours, some 6,
etc. Instead of having everyone make themselves sick screwing around
with timing to find out what they can "get away with," I just say 4
hours because 95+% of people are fine with that.
Andy . .. . . . . . . . . .. . . . . . .
In de interview die Mark poste eerder van Andy, hij zei dat de halfwaardetijd van ALA is 1,5 tot 2,5h, afhankelijk van je metabolisme. Dus als je de ALA snel metaboliseerd, en je 3 of 4uur doseert, dan krijg je herdistributie bij elke dose. Daarom kan je beter elke 2uur doseren, of zelfs korter.
Ik ben voorstander van langere rondes, indien mogelijk. Ik neem nu 12,5mg ALA, en ik wil het snel verhogen, als mijn gal productie dat toelaat.
Ik ben benieuwd how het met jullie gaat.